Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT

Ireneusz Grulkowski; Grzegorz Wilczynski; Danuta Bukowska; Maciej Szkulmowski; Jakub Wlodarczyk; Karol Karnowski; Daniel Ruminski; Andrzej Kowalczyk; Maciej Wojtkowski

doi:10.1117/12.875212

23 March 2011 Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT

Ireneusz Grulkowski, Grzegorz Wilczynski, Danuta Bukowska, Maciej Szkulmowski, Jakub Wlodarczyk, Karol Karnowski, Daniel Ruminski, Andrzej Kowalczyk, Maciej Wojtkowski

Author Affiliations +

Proceedings Volume 7883, Photonic Therapeutics and Diagnostics VII; 788342 (2011) https://doi.org/10.1117/12.875212
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

We have developed and applied a high-speed Spectral OCT system to image small animal brains. OCT imaging with high spatial resolution and application of multi-parameter approach enabled cortical blood flow visualization. We imaged the brain vascular network of an anesthetized mouse stroke model. We demonstrated the impact of induced stroke on the brain vasculature. The preliminary studies have revealed local ischemia in the areas of the stroke.

Citation Download Citation

Ireneusz Grulkowski, Grzegorz Wilczynski, Danuta Bukowska, Maciej Szkulmowski, Jakub Wlodarczyk, Karol Karnowski, Daniel Ruminski, Andrzej Kowalczyk, and Maciej Wojtkowski "Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT", Proc. SPIE 7883, Photonic Therapeutics and Diagnostics VII, 788342 (23 March 2011); https://doi.org/10.1117/12.875212

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Optical coherence tomography

Brain

Blood circulation

Doppler effect

Visualization

Neuroimaging

Scanners

Show All Keywords

Keywords/Phrases

Search In:

Publication Years