The morphology of apoptosis and necrosis of fat cells after photodynamic treatment at a constant temperature in vitro

Irina Yu. Yanina; Tatyana G. Orlova; Valery V. Tuchin; Gregory B. Altshuler

doi:10.1117/12.878754

17 February 2011 The morphology of apoptosis and necrosis of fat cells after photodynamic treatment at a constant temperature in vitro

Irina Yu. Yanina, Tatyana G. Orlova, Valery V. Tuchin, Gregory B. Altshuler

Author Affiliations +

Proceedings Volume 7887, Mechanisms for Low-Light Therapy VI; 78870X (2011) https://doi.org/10.1117/12.878754
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

Photodynamic therapy with temperature control is a new approach for treatment of obesity and cellulite. Cell death can occur under the action of various physical, chemical and biological factors. Depending on the inductor, this is apoptosis or necrosis. These two forms of cell death differ on the biochemical and morphological levels. Biochemical changes occur quickly enough and it raises difficulties of their detection. One of the morphological characteristics of apoptosis is a decrease (contraction) of cells, and necrosis - an increase in the size of the cell (swelling). This attribute simply determined visually using a digital microscope. The program was designed using LabVEIW media, which allowed us to develop the software for providing interaction with the measuring and control equipment, data collection, processing and displaying the information and results of calculations and simulations for the individual cells and ensembles of cells, and, in general, to automate process.

Citation Download Citation

Irina Yu. Yanina, Tatyana G. Orlova, Valery V. Tuchin, and Gregory B. Altshuler "The morphology of apoptosis and necrosis of fat cells after photodynamic treatment at a constant temperature in vitro", Proc. SPIE 7887, Mechanisms for Low-Light Therapy VI, 78870X (17 February 2011); https://doi.org/10.1117/12.878754

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