8 March 2011 Full-field optical coherence tomography for rapid 3-D imaging in biological systems
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Full-field optical coherence tomography (FF-OCT) is an emerging non-invasive, label-free, interferometric technique for 3D imaging of biomedical objects with micron-scale resolutions. The conventional phase-shifting technique in FF-OCT involves in mechanically moving a mirror to change the optical path difference for obtaining en face OCT images, but with the use of a broadband source in FF-OCT, the phase shifts of different spectral components are not the same, resulting in the ambiguities in 3-D image reconstruction. In this study, we propose to utilize the ferroelectric liquid crystal (FLC) device-controlled geometric phase shifting technique to realize achromatic phase shifting for rapid 3-D imaging. We demonstrate this FLC-controlled FF-OCT technique by imaging biological samples (e.g., onion tissue).
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Wei Zheng, Colin J. R. Sheppard, "Full-field optical coherence tomography for rapid 3-D imaging in biological systems", Proc. SPIE 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV, 78892M (8 March 2011); doi: 10.1117/12.874895; https://doi.org/10.1117/12.874895

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