10 February 2011 Integrated scanning laser ophthalmoscopy and optical coherence tomography for quantitative multimodal imaging of retinal degeneration and autofluorescence
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Proceedings Volume 7892, Multimodal Biomedical Imaging VI; 789209 (2011) https://doi.org/10.1117/12.873982
Event: SPIE BiOS, 2011, San Francisco, California, United States
Abstract
Scanning Laser Ophthalmoscopy (SLO) and Coherence Tomography (OCT) are complimentary retinal imaging modalities. Integration of SLO and OCT allows for both fluorescent detection and depth- resolved structural imaging of the retinal cell layers to be performed in-vivo. System customization is required to image rodents used in medical research by vision scientists. We are investigating multimodal SLO/OCT imaging of a rodent model of Stargardt's Macular Dystrophy which is characterized by retinal degeneration and accumulation of toxic autofluorescent lipofuscin deposits. Our new findings demonstrate the ability to track fundus autofluorescence and retinal degeneration concurrently.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ali Issaei, Ali Issaei, Lukasz Szczygiel, Lukasz Szczygiel, Nima Hossein-Javaheri, Nima Hossein-Javaheri, Mei Young, Mei Young, L. L. Molday, L. L. Molday, R. S. Molday, R. S. Molday, M. V. Sarunic, M. V. Sarunic, } "Integrated scanning laser ophthalmoscopy and optical coherence tomography for quantitative multimodal imaging of retinal degeneration and autofluorescence", Proc. SPIE 7892, Multimodal Biomedical Imaging VI, 789209 (10 February 2011); doi: 10.1117/12.873982; https://doi.org/10.1117/12.873982
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