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10 February 2011 MRI-guided fluorescence tomography of PPIX in the breast: a case study
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Proceedings Volume 7892, Multimodal Biomedical Imaging VI; 78920M (2011)
Event: SPIE BiOS, 2011, San Francisco, California, United States
A case study to demonstrate fluorescence tomography of endogenous protoporphyrin IX (PPIX) in breast cancer is presented. An MRI-coupled fluorescence tomography system with spectrometer detectors was used to acquire excitation and emission data through the breast of a human subject undergoing chemotherapy for breast cancer. Volumetric images of PPIX fluorescence showed elevated levels of fluorescence activity in the fibro-glandular tissue as compared to the adipose tissue. Fluorescence levels in the tumor were higher than in the adipose tissue but lower than the fibro-glandular tissue.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Scott C. Davis, Michael A. Mastanduno, Brian W. Pogue, and Keith D. Paulsen "MRI-guided fluorescence tomography of PPIX in the breast: a case study", Proc. SPIE 7892, Multimodal Biomedical Imaging VI, 78920M (10 February 2011);

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