For in vivo medical applications, endoscopy shows great potential for its minimally invasive manner,
flexibility and close-up imaging characteristic. A miniaturized imaging probe combining ultrasound and
photoacoustic endoscopy has been developed. The output of a 532-nm pulse laser was coupled into and
delivered to the probe by a 200-micron-core multimode fiber. A 40 MHz ring shape ultrasound transducer
was fabricated to receive pulse echo ultrasound and photoacoustic signals as well. The light-guiding optical
fiber, the ring ultrasound transducer, and a mirror-based reflective material for the coaxial laser beam and
ultrasound signal were integrated into the probe with a final packaged diameter of 2.5 mm. The
performance of the probe was tested by imaging a graphite rod. The imaging ability of this dual-modality
system was demonstrated by imaging the cross section of a rabbit aorta.
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Wei Wei, Xiang Li, Qifa Zhou, K. Kirk Shung, Zhongping Chen, "Development of a combined ultrasound and photoacoustic endoscopic probe," Proc. SPIE 7893, Endoscopic Microscopy VI, 789317 (22 February 2011);