16 February 2011 Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy
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Proceedings Volume 7895, Optical Biopsy IX; 789502 (2011) https://doi.org/10.1117/12.871718
Event: SPIE BiOS, 2011, San Francisco, California, United States
Abstract
The potential of autofluorescence microscopy under ultraviolet excitation is investigated as a method to visualize superficial epithelial microstructures and their modification with progression of disease. This method does not require the use of contrast agents, sectioning methods, or tissue preparation. Imaging of esophagus tissue is the focus of this study and deals with three main issues: a) What is the origin of the signal; b) How the gradual microstructure modification associated with various stages of esophageal disease is visualized; c) What are the designing parameters for in vivo implementation.
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Bevin Lin, Bevin Lin, Shiro Urayama, Shiro Urayama, Ramez M. G. Saroufeem, Ramez M. G. Saroufeem, Dennis L. Matthews, Dennis L. Matthews, Stavros G. Demos, Stavros G. Demos, } "Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy", Proc. SPIE 7895, Optical Biopsy IX, 789502 (16 February 2011); doi: 10.1117/12.871718; https://doi.org/10.1117/12.871718
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