Near-infrared optical mammography with broadband spectral imaging for spatially resolved oximetry

Yang Yu; Angelo Sassaroli; Marc J. Homer; Roger A. Graham; Sergio Fantini

doi:10.1117/12.873945

17 February 2011 Near-infrared optical mammography with broadband spectral imaging for spatially resolved oximetry

Yang Yu, Angelo Sassaroli, Marc J. Homer, Roger A. Graham, Sergio Fantini

Proceedings Volume 7896, Optical Tomography and Spectroscopy of Tissue IX; 78962G (2011) https://doi.org/10.1117/12.873945
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

We report the development of an instrument for diffuse spectral imaging of the human breast operating over the wavelength range 650-900 nm. This instrument images the slightly compressed human breast in a planar geometry by performing a tandem scan, over the x-y plane, of a 3 mm illumination optical fiber and a 5 mm collection optical fiber that are collinear and located on opposite sides of the breast. An edge-correction algorithm accounts for breast thickness variability over the x-y plane, a second-derivative imaging algorithm enhances the display of optical inhomogeneities, and a paired-wavelength spectral method yields oxygenation maps. We report our results of oxygenation mapping in eighteen human subjects, two of which are breast cancer patients, one with a ductal carcinoma in situ, the other with an invasive ductal carcinoma.

Citation Download Citation

Yang Yu, Angelo Sassaroli, Marc J. Homer, Roger A. Graham, and Sergio Fantini "Near-infrared optical mammography with broadband spectral imaging for spatially resolved oximetry", Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 78962G (17 February 2011); https://doi.org/10.1117/12.873945

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available