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18 February 2011 Temperature increase of ex vivo corneas from multiple 2.01-micron incident laser pulses
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Current laser safety standards for multiple pulse lasers are based primarily on modeling and the results of single pulse studies. Previous thermal effects studies have focused on histological and visible endpoints, with only a few studies examining the actual temperatures achieved. The goal of this research was to probe the actual vertical temperature profile produced by 2.01 micron laser pulses in the cornea. In this study the corneal temperature rise from multiple 2.01 micron Tm:YAG laser pulses was investigated using ex-vivo rabbit eyes. A thermal-measurement data set for a different number of pulses was collected and compared. An infrared thermal camera employing microbolometer detectors captured surface temperature rises resulting from laser pulses. Single 10 ms pulses as well as two, three, and four pulse sequences were utilized while the total energy delivered was held constant. A comparison of the data to temperatures required for denaturing proteins and the current laser safety guidelines will be presented.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Edward Kelly and Thomas Johnson "Temperature increase of ex vivo corneas from multiple 2.01-micron incident laser pulses", Proc. SPIE 7897, Optical Interactions with Tissue and Cells XXII, 78970J (18 February 2011);

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