18 February 2011 Determining the optical properties in a fibrous turbid medium
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Abstract
Light propagation in fibrous biological tissue is quite different from that in isotropic medium. Several studies showed that the measured reduced scattering coefficient in fibrous tissue strongly depends on the measurement direction. In this study, we investigated the possibility of retrieving optical properties in anisotropic tissue using time-domain measurements. A Monte Carlo model was used to simulate light propagation in a fibrous tissue consisting of aligned cylinders and spherical shape scatters. An isotropic diffuse model was then used to determine the optical properties from simulated time-resolved reflectance. When the measurement position was parallel to the fiber direction, the derived reduced scattering coefficient had good agreement with the true background scattering coefficient values with a less than 10% error. In contrast, when measuring in a direction perpendicular to the cylinders, the derived reduced scattering coefficient was close to the summation of the reduced scattering coefficients of both cylinders and background only in samples with small cylinder diameters. If the fiber size in the medium is known, the reduced scattering coefficient associated with the cylinders can be derived by using a correction coefficient.
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Ali Shuaib, Gang Yao, "Determining the optical properties in a fibrous turbid medium", Proc. SPIE 7897, Optical Interactions with Tissue and Cells XXII, 78970Q (18 February 2011); doi: 10.1117/12.873007; https://doi.org/10.1117/12.873007
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