11 April 2011 Photoacoustic imaging for deep targets in the breast using a multichannel 2D array transducer
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A photoacoustic (PA) imaging system was developed to achieve high sensitivity for the detection and characterization of vascular anomalies in the breast in the mammographic geometry. Signal detection from deep in the breast was achieved by a broadband 2D PVDF planar array that has a round shape with one side trimmed straight to improve fit near the chest wall. This array has 572 active elements and a -6dB bandwidth of 0.6-1.7 MHz. The low frequency enhances imaging depth and increases the size of vascular collections displayed without edge enhancement. The PA signals from all the elements go through low noise preamplifiers in the probe that are very close to the array elements for optimized noise control. Driven by 20 independent on-probe signal processing channels, imaging with both high sensitivity and good speed was achieved. To evaluate the imaging depth and the spatial resolution of this system,2.38mm I.D. artificial vessels embedded deeply in ex vivo breasts harvested from fresh cadavers and a 3mm I.D. tube in breast mimicking phantoms made of pork loin and fat tissues were imaged. Using near-infrared laser light with incident energy density within the ANSI safety limit, imaging depths of up to 49 mm in human breasts and 52 mm in phantoms were achieved. With a high power tunable laser working on multiple wavelengths, this system might contribute to 3D noninvasive imaging of morphological and physiological tissue features throughout the breast.
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Zhixing Xie, Xueding Wang, Richard F. Morris, Frederic R. Padilla, Gerald L. Lecarpentier, and Paul L. Carson "Photoacoustic imaging for deep targets in the breast using a multichannel 2D array transducer", Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 789907 (11 April 2011); doi: 10.1117/12.875138; https://doi.org/10.1117/12.875138

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