Image processing and analysis in a dual-modality optoacoustic/ultrasonic system for breast cancer diagnosis

Vyacheslav Nadvoretskiy; Sergey Ermilov; Hans-Peter Brecht; Richard Su; Alexander Oraevsky

doi:10.1117/12.877389

11 April 2011 Image processing and analysis in a dual-modality optoacoustic/ultrasonic system for breast cancer diagnosis

Vyacheslav Nadvoretskiy, Sergey Ermilov, Hans-Peter Brecht, Richard Su, Alexander Oraevsky

Author Affiliations +

Proceedings Volume 7899, Photons Plus Ultrasound: Imaging and Sensing 2011; 789909 (2011) https://doi.org/10.1117/12.877389
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

Coregistered optoacoustic (OA) and ultrasound (US) images obtained using a dual modality optoacoustic/ultrasonic breast imaging system are used together for enhanced diagnostic capabilities in comparison to each individual technology. Therefore, an operator-independent delineation of diagnostically relevant objects (in our case breast tumors) with subsequent automatic analysis of image features is required. We developed the following procedure: 1) Image filtering is implemented on a US image to minimize speckle noise and simultaneously preserve the sharpness of the boundaries of the extended objects; 2) Boundaries of the objects of interest are automatically delineated starting with an initial guess made by an operator; 3) Both US and OA images are analyzed using the detected boundaries (contrast, boundary sharpness, homogeneity of the objects and background, boundary morphology parameters are calculated). Calculated image characteristics can be used for statistically independent evaluation of structural information (US data) and vascularization (OA data) of the studied breast tissues. Operator-independent delineation of the objects of interest (e.g. tumors and blood vessels) is essential in clinical OA spectroscopy (using multiple laser wavelengths to quantify concentrations of particular tissue chromophores, such as oxy- and deoxy- hemoglobin, water, and lipids). Another potential application of the suggested image analysis algorithm could be in OA imaging system design, when system performance should be evaluated in terms of quality of the images reconstructed from the well-defined objects of interest. The discussed principles of image analysis are illustrated by using real clinical US and OA data.

Citation Download Citation

Vyacheslav Nadvoretskiy, Sergey Ermilov, Hans-Peter Brecht, Richard Su, and Alexander Oraevsky "Image processing and analysis in a dual-modality optoacoustic/ultrasonic system for breast cancer diagnosis", Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 789909 (11 April 2011); https://doi.org/10.1117/12.877389

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available