17 February 2011 Imaging the small animal cardiovascular system in real-time with multispectral optoacoustic tomography
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Abstract
Multispectral Optoacoustic Tomography (MSOT) is an emerging technique for high resolution macroscopic imaging with optical and molecular contrast. We present cardiovascular imaging results from a multi-element real-time MSOT system recently developed for studies on small animals. Anatomical features relevant to cardiovascular disease, such as the carotid arteries, the aorta and the heart, are imaged in mice. The system's fast acquisition time, in tens of microseconds, allows images free of motion artifacts from heartbeat and respiration. Additionally, we present in-vivo detection of optical imaging agents, gold nanorods, at high spatial and temporal resolution, paving the way for molecular imaging applications.
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Adrian Taruttis, Adrian Taruttis, Eva Herzog, Eva Herzog, Daniel Razansky, Daniel Razansky, Vasilis Ntziachristos, Vasilis Ntziachristos, } "Imaging the small animal cardiovascular system in real-time with multispectral optoacoustic tomography", Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 789913 (17 February 2011); doi: 10.1117/12.874242; https://doi.org/10.1117/12.874242
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