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22 February 2011 Forward model of thermally-induced acoustic signal specific to intralumenal detection geometry
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This work investigates a forward model associated with intra-lumenal detection of acoustic signal originated from transient thermal-expansion of the tissue. The work is specific to intra-lumenal thermo-acoustic tomography (TAT) which detects the contrast of tissue dielectric properties with ultrasonic resolution, but it is also extendable to intralumenal photo-acoustic tomography (PAT) which detects the contrast of light absorption properties of tissue with ultrasound resolution. Exact closed-form frequency-domain or time-domain forward model of thermally-induced acoustic signal have been studied rigorously for planar geometry and two other geometries, including cylindrical and spherical geometries both of which is specific to external-imaging, i.e. breast or brain imaging using an externally-deployed applicator. This work extends the existing studies to the specific geometry of internal or intra-lumenal imaging, i.e., prostate imaging by an endo-rectally deployed applicator. In this intra-lumenal imaging geometry, both the source that excites the transient thermal-expansion of the tissue and the acoustic transducer that acquires the thermally-induced acoustic signal are assumed enclosed by the tissue and on the surface of a long cylindrical applicator. The Green's function of the frequency-domain thermo-acoustic equation in spherical coordinates is expanded to cylindrical coordinates associated with intra-lumenal geometry. Inverse Fourier transform is then applied to obtain a time-domain solution of the thermo-acoustic pressure wave for intra-lumenal geometry. Further employment of the boundary condition to the "convex" applicator-tissue interface would render an exact forward solution toward accurate reconstruction for intra-lumenal thermally-induced acoustic imaging.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sovanlal Mukherjee, Charles F. Bunting, and Daqing Piao "Forward model of thermally-induced acoustic signal specific to intralumenal detection geometry", Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 789936 (22 February 2011);

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