Translator Disclaimer
23 February 2011 Modelling and characterization of photothermal effects assisted with gold nanorods in ex vivo samples and in a murine model
Author Affiliations +
Abstract
We discuss in this article the implementation of a laser-tissue interaction and bioheat-transfer 2-D finite-element model for Photothermal Therapy assisted with Gold Nanorods. We have selected Gold Nanorods as absorbing nanostructures in order to improve the efficiency of using compact diode lasers because of their high opto-thermal conversion efficiency at 808 and 850 nm. The goal is to model the distribution of the optical energy among the tissue including the skin absorption effects and the tissue thermal response, with and without the presence of Gold Nanorods. The heat generation due to the optical energy absorption and the thermal propagation will be computationally modeled and optimized. The model has been evaluated and compared with experimental ex-vivo data in fresh chicken muscle samples and in-vivo BALB/c mice animal model.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Horacio Lamela Rivera, Félix Rodríguez Jara, and Vincent Cunningham "Modelling and characterization of photothermal effects assisted with gold nanorods in ex vivo samples and in a murine model", Proc. SPIE 7901, Energy-based Treatment of Tissue and Assessment VI, 79010D (23 February 2011); https://doi.org/10.1117/12.875706
PROCEEDINGS
10 PAGES


SHARE
Advertisement
Advertisement
Back to Top