23 February 2011 Experimental characterization of a SonoKnife applicator
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The SonoKnife is a scan-able high intensity line-focused ultrasound device for thermal ablation (52 - 60°C) of superficially located advanced tumors or nodal disease in the head and neck. Based on preliminary simulation results, a prototype cylindrical section transducer operating at 3.5 MHz, with a 60 mm radius of curvature, an elevation of 30 mm and an aperture of 60 mm, was constructed for laboratory testing. The three-dimensional distribution of the acoustic field was measured in water and compared to preliminary numerical results. Ablation experiments were performed in gel phantoms, in porcine liver ex vivo and in live piglets. The experimental results agreed well with the theoretical simulations and showed that the SonoKnife transducer had a narrow acoustic edge and is able to ablate living biological tissues at practical power levels.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Rongmin Xia, Rongmin Xia, Duo Chen, Duo Chen, Gal Shafirstein, Gal Shafirstein, Xin Chen, Xin Chen, Peter Corry, Peter Corry, Robert Griffin, Robert Griffin, Eduardo G. Moros, Eduardo G. Moros, } "Experimental characterization of a SonoKnife applicator", Proc. SPIE 7901, Energy-based Treatment of Tissue and Assessment VI, 79010Q (23 February 2011); doi: 10.1117/12.876379; https://doi.org/10.1117/12.876379

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