10 February 2011 Mapping skin using Raman spectroscopy
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In this work we carried out a comparison and localization of skin Raman spectra. Measurements were made in regions where Raman scatter is caused by the excitation source; we used the spectra overlap in a comparative way. Ten volunteers with different skin colors participated in the experiment; body parts sampled were palm and dorsum of the hand. The excitation wavelength used for this work was 785nm. A spectrometer with 6cm-1 resolution and spectral region range 0 to 2000 cm-1 was utilized. We used Matlab® to overlap and compare the differences between Raman spectra form different samples. We found spectral variations that were caused by differences on the surface of the skin, such as scars and moles. This work helps to identify potential undesirable behavior on the epidermis.
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A. E. Villanueva-Luna, J. Castro-Ramos, S. Vazquez-Montiel, A. Flores-Gil, J. A. Delgado Atencio, C. M. Ortiz-Lima, "Mapping skin using Raman spectroscopy", Proc. SPIE 7906, Optical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III, 790610 (10 February 2011); doi: 10.1117/12.874268; https://doi.org/10.1117/12.874268

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