14 February 2011 Robust detection of peak signals for lateral flow immunoassays
Author Affiliations +
Template matching method is presented to identify the peaks from the scanned signals of lateral flow immunoassay strips. The template is composed of two pulses separated by the distance of the control and the target ligand line in the assay, and is convolved with the scanned signal to deliver the maximum at the center of the two peaks. The peak regions were identified with the predefined distances from the center. Glycosylated haemoglobin immunoassay strips and fluorescent strip readers from Boditechmed Inc. were tested to estimate the lot and reader variations of the concentration measurands. The results showed the robustness of the propose method.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Jongwon Kim, Jongwon Kim, Jong Dae Kim, Jong Dae Kim, Kie Bong Nahm, Kie Bong Nahm, Eui Yul Choi, Eui Yul Choi, Geumyoung Lee, Geumyoung Lee, } "Robust detection of peak signals for lateral flow immunoassays", Proc. SPIE 7929, Microfluidics, BioMEMS, and Medical Microsystems IX, 792910 (14 February 2011); doi: 10.1117/12.876260; https://doi.org/10.1117/12.876260

Back to Top