NIR DLP hyperspectral imaging system for medical applications

Eleanor Wehner; Abhas Thapa; Edward Livingston; Karel Zuzak

doi:10.1117/12.875802

11 February 2011 NIR DLP hyperspectral imaging system for medical applications

Eleanor Wehner, Abhas Thapa, Edward Livingston, Karel Zuzak

Proceedings Volume 7932, Emerging Digital Micromirror Device Based Systems and Applications III; 793204 (2011) https://doi.org/10.1117/12.875802
Event: SPIE MOEMS-MEMS, 2011, San Francisco, California, United States

Abstract

DLP® hyperspectral reflectance imaging in the visible range has been previously shown to quantify hemoglobin oxygenation in subsurface tissues, 1 mm to 2 mm deep. Extending the spectral range into the near infrared reflects biochemical information from deeper subsurface tissues. Unlike any other illumination method, the digital micro-mirror device, DMD, chip is programmable, allowing the user to actively illuminate with precisely predetermined spectra of illumination with a minimum bandpass of approximately 10 nm. It is possible to construct active spectral-based illumination that includes but is not limited to containing sharp cutoffs to act as filters or forming complex spectra, varying the intensity of light at discrete wavelengths. We have characterized and tested a pure NIR, 760 nm to 1600 nm, DLP hyperspectral reflectance imaging system. In its simplest application, the NIR system can be used to quantify the percentage of water in a subject, enabling edema visualization. It can also be used to map vein structure in a patient in real time. During gall bladder surgery, this system could be invaluable in imaging bile through fatty tissue, aiding surgeons in locating the common bile duct in real time without injecting any contrast agents.

Citation Download Citation

Eleanor Wehner, Abhas Thapa, Edward Livingston, and Karel Zuzak "NIR DLP hyperspectral imaging system for medical applications", Proc. SPIE 7932, Emerging Digital Micromirror Device Based Systems and Applications III, 793204 (11 February 2011); https://doi.org/10.1117/12.875802

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