17 January 2011 High-sensitive nonlinear detection of steroids by resonant double grating waveguide structures-based immunosensors
Author Affiliations +
Abstract
We report the non linear fluorescence real-time detection of methylboldenone, an androgenic anabolic steroid used illegally as growth promoter based on a resonant sensing chip: a double grating waveguide structure. The limit of detection of this synthetic steroid is two orders of magnitude lower than the Minimum Required Performance Limit required by the World Anti-Doping Agency. The immunoreagents have been have been immobilized onto the surface of the resonant sensor after being activated with phosphonohexanoic acid spacers. The developed immunosensor presents great potential as a robust sensing device for fast and early detection of illegal dopants and food contaminants.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Alejandro Muriano, Alejandro Muriano, J.-Pablo Salvador, J.-Pablo Salvador, Roger Galve, Roger Galve, M.-Pilar Marco, M.-Pilar Marco, Anisha Thayil K.N., Anisha Thayil K.N., Pablo Loza-Alvarez, Pablo Loza-Alvarez, Silvia Soria, Silvia Soria, } "High-sensitive nonlinear detection of steroids by resonant double grating waveguide structures-based immunosensors", Proc. SPIE 7941, Integrated Optics: Devices, Materials, and Technologies XV, 794114 (17 January 2011); doi: 10.1117/12.876456; https://doi.org/10.1117/12.876456
PROCEEDINGS
7 PAGES


SHARE
Back to Top