16 March 2011 Observing the high resolution capabilities of a silicon PET insert probe
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Abstract
A high resolution silicon detector probe in coincidence with a conventional PET scanner should be able to increase the scanner's spatial resolution. The MADEIRA PET probe is such a device and was simulated in coincidence with a clinical scanner was simulated using the Monte Carlo package GATE. The device consists of ten layers of silicon of 1x1x1 mm3 pixels in a 80x52 array. Simulations were run with various activity distributions. No attenuation was included to reduce the amount of scatter in the simulated data. The simulations were conducted in air. Coincidence sorting was performed on the singles list mode data. Random coincidences were rejected and no time or energy blurring was used in order to isolate the events which determine the highest achievable spatial resolution. Sinograms where calculated from the sorted data with one sinogram containing events where both annihilation photons were detected in the PET ring and another for probe-ring events. The probe-ring sinograms identified the limited FOV of the probe. The point-spread function was calculated from the sinograms. The full-width half-maximum decreased from 5.5 mm in the ring-ring sinogram to 2.7 mm in the ring-probe sinogram. The full-width third-maximum decreased from 7 mm to 3 mm. Images were reconstructed using the Maximum Likelihood-Expectation Maximization (ML-EM) algorithm using the list-mode coincidence data. The improvement in spatial resolution seen in the sinograms is reflected in the images.
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K. Brzezinski, K. Brzezinski, J. F. Oliver, J. F. Oliver, J. Gillam, J. Gillam, C. Lacasta, C. Lacasta, M. Rafecas, M. Rafecas, } "Observing the high resolution capabilities of a silicon PET insert probe", Proc. SPIE 7961, Medical Imaging 2011: Physics of Medical Imaging, 796146 (16 March 2011); doi: 10.1117/12.878198; https://doi.org/10.1117/12.878198
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