9 March 2011 Development of a field free line magnet for projection MPI
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The field free line (FFL) magnet has the potential to greatly increase signal to noise ratio (SNR) or to decrease scan time for magnetic particle imaging (MPI). The use of an FFL will decrease scan time by reducing image dimensionality from a 3D image to a projection image. Alternatively, in comparison to a 3D scan of equal scan time, an FFL scanner will increase SNR through more signal averages. An FFL magnet would enable projection imaging as is used in projection x-ray and is common in angiography. The Philips and Lubeck groups have pioneered the design of field free line magnets for MPI and have shown that they can achieve power efficiency similar to that of a field free point, the standard in MPI. Current FFL magnet designs have not been optimized for characteristics such as gradient efficiency and gradient magnitude homogeneity. This work shows a 2.25 T/m Halbach quadrupole permanent magnet design that produces a homogeneous magnetic field along the field free line. Along the FFL, we experimentally measured a field maximum of 2mT within the imaging field of view (FOV), and we experimentally measured that the gradient perpendicular to the FFL deviates by a maximum of 3.4%. In future work, we plan to produce an x-space MPI image using the FFL magnet. We also plan to improve upon this design using optimization techniques.
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Justin Konkle, Patrick Goodwill, Steven Conolly, "Development of a field free line magnet for projection MPI", Proc. SPIE 7965, Medical Imaging 2011: Biomedical Applications in Molecular, Structural, and Functional Imaging, 79650X (9 March 2011); doi: 10.1117/12.878435; https://doi.org/10.1117/12.878435

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