Validation of a new digital breast tomosynthesis medical display

Cédric Marchessoux; Nicolas Vivien; Asli Kumcu; Tom Kimpe

doi:10.1117/12.873196

3 March 2011 Validation of a new digital breast tomosynthesis medical display

Cédric Marchessoux, Nicolas Vivien, Asli Kumcu, Tom Kimpe

Proceedings Volume 7966, Medical Imaging 2011: Image Perception, Observer Performance, and Technology Assessment; 79660R (2011) https://doi.org/10.1117/12.873196
Event: SPIE Medical Imaging, 2011, Lake Buena Vista (Orlando), Florida, United States

Abstract

The main objective of this study is to evaluate and validate the new Barco medical display MDMG-5221 which has been optimized for the Digital Breast Tomosynthesis (DBT) imaging modality system, and to prove the benefit of the new DBT display in terms of image quality and clinical performance. The clinical performance is evaluated by the detection of micro-calcifications inserted in reconstructed Digital Breast Tomosynthesis slices. The slices are shown in dynamic cine loops, at two frames rates. The statistical analysis chosen for this study is the Receiver Operating Characteristic Multiple-Reader, Multiple-Case methodology, in order to measure the clinical performance of the two displays. Four experienced radiologists are involved in this study. For this clinical study, 50 normal and 50 abnormal independent datasets were used. The result is that the new display outperforms the mammography display for a signal detection task using real DBT images viewed at 25 and 50 slices per second. In the case of 50 slices per second, the p-value = 0.0664. For a cut-off where alpha=0.05, the conclusion is that the null hypothesis cannot be rejected, however the trend is that the new display performs 6% better than the old display in terms of AUC. At 25 slices per second, the difference between the two displays is very apparent. The new display outperforms the mammography display by 10% in terms of AUC, with a good statistical significance of p=0.0415.

Citation Download Citation

Cédric Marchessoux, Nicolas Vivien, Asli Kumcu, and Tom Kimpe "Validation of a new digital breast tomosynthesis medical display", Proc. SPIE 7966, Medical Imaging 2011: Image Perception, Observer Performance, and Technology Assessment, 79660R (3 March 2011); https://doi.org/10.1117/12.873196

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