25 March 2011 Breast imaging with ultrasound tomography: update on a comparative study with MR
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The objective of this study is to present imaging parameters and display thresholds of an ultrasound tomography (UST) prototype in order to demonstrate analogous visualization of overall breast anatomy and lesions relative to magnetic resonance (MR). Thirty-six women were imaged with MR and our UST prototype. The UST scan generated sound speed, attenuation, and reflection images and were subjected to variable thresholds then fused together into a single UST image. Qualitative and quantitative comparisons of MR and UST images were utilized to identify anatomical similarities and mass characteristics. Overall, UST demonstrated the ability to visualize and characterize breast tissues in a manner comparable to MR without the use of IV contrast. For optimal visualization, fused images utilized thresholds of 1.46±0.1 km/s for sound speed to represent architectural features of the breast including parenchyma. An arithmetic combination of images using the logical .AND. and .OR. operators, along with thresholds of 1.52±0.03 km/s for sound speed and 0.16±0.04 dB/cm for attenuation, allowed for mass detection and characterization similar to MR.
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Bryan Ranger, Bryan Ranger, Peter Littrup, Peter Littrup, Neb Duric, Neb Duric, Cuiping Li, Cuiping Li, Steven Schmidt, Steven Schmidt, Olsi Rama, Olsi Rama, Lisa Bey-Knight, Lisa Bey-Knight, } "Breast imaging with ultrasound tomography: update on a comparative study with MR", Proc. SPIE 7968, Medical Imaging 2011: Ultrasonic Imaging, Tomography, and Therapy, 79680M (25 March 2011); doi: 10.1117/12.878922; https://doi.org/10.1117/12.878922

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