25 March 2011 A practical, robust approach to high-resolution breast ultrasound tomography
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Breast ultrasound tomography has the potential to improve the cost, safety and reliability of breast cancer screening and diagnosis over the gold-standard of mammography. Vital to achieving this potential is the development of imaging algorithms to unravel the complex anatomy of the breast and its mechanical properties. The solution most commonly relied upon is Time-of-Flight Tomography but this exhibits low resolution due to the presence of diffraction effects. Iterative full-wave inversion methods present one solution to achieve higher resolution, but these are slow and are not guaranteed to converge to the correct solution. Presented here is HARBUT, the Hybrid Algorithm for Robust Breast Ultrasound Tomography, which utilises the complementary strengths of Time-of-Flight and Diffraction Tomography resulting in a direct, fast, robust and accurate high resolution method of reconstructing the sound-speed through the breast. The new algorithm is shown to produce accurate reconstructions with realistic data from a complex 3D simulation, with masses as small as 4mm being clearly visible.
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P. Huthwaite and F. Simonetti "A practical, robust approach to high-resolution breast ultrasound tomography", Proc. SPIE 7968, Medical Imaging 2011: Ultrasonic Imaging, Tomography, and Therapy, 79680S (25 March 2011); doi: 10.1117/12.878690; https://doi.org/10.1117/12.878690

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