21 October 2011 High resolution confocal polarimeter for the living human retina
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Abstract
There is strong evidence that the living human retina has polarization signatures that could be linked to the presence of Glaucoma, an ocular disease that is the second cause of blindness in the western world. In a polarization sensitive ophthalmoscope, the amount of light that can be used is limited for the safety of the subject, and the return is typically a small fraction of the light used for illumination, of the order of 10-6. Furthermore, the acquisition rates have to be sufficiently fast to avoid eye-movement artifacts. The light-budget available to produce a polarization image with a scanning laser ophthalmoscope is typically in the order of 10 nW, and pixel acquisition sampling rates are of several MHz. We are currently developing an imaging instrument for vision research and clinical vision applications and aim to introduce it to the medical and clinical environment using objective methods of image quality assessment. Here we discuss the stringent imaging requirements, polarimeter design, and show high resolution polarization retinal images.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
D. Lara, C. Paterson, "High resolution confocal polarimeter for the living human retina", Proc. SPIE 8011, 22nd Congress of the International Commission for Optics: Light for the Development of the World, 80110E (21 October 2011); doi: 10.1117/12.901777; https://doi.org/10.1117/12.901777
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