2 November 2011 Determination of coagulation time of human blood by biospeckle technique
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When a lesion occurs in a blood vessel, a series of mechanisms are activated to stop hemorrhage by increasing blood viscosity at the wounded place. If a sample of blood extracted of the human body is illuminated with coherent light, a time varying speckle pattern is observed. It is show high activity at the start and decreases with time until it finally stop. The analysis of these patterns shows a degree of correlation between speckle activity and the temporal evolution of the clot. These preliminary results are promising for the continuation of studies aiming to the application of biospeckle techniques to the analysis of coagulation times.
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Mario Milver Patiño Velasco, Jairo Alfonso Vásquez Lopez, Carlos Augusto Andrade Erazo, Ricardo Arizaga, Héctor Rabal, Marcelo Trivi, "Determination of coagulation time of human blood by biospeckle technique", Proc. SPIE 8011, 22nd Congress of the International Commission for Optics: Light for the Development of the World, 80118S (2 November 2011); doi: 10.1117/12.902185; https://doi.org/10.1117/12.902185

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