26 May 2011 Temperature elevations in prostatic tumors during laser photothermal therapy
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Proceedings Volume 8025, Smart Biomedical and Physiological Sensor Technology VIII; 80250G (2011); doi: 10.1117/12.882746
Event: SPIE Defense, Security, and Sensing, 2011, Orlando, Florida, United States
Abstract
In vivo experiments were performed to measure temperature elevations in prostatic tumors implanted in mice during laser photothermal therapy using nanorods. Ti:Sapphire laser tuned at 800 nm irradiating the surface of the tumor delivered an average laser power of 0.5 - 1.0 W, equivalent to a laser radiance of 1.3-2.6 W/cm2. The temperature elevations measured by two thermocouples located at the center and bottom of the tumor have shown non-uniform tumor temperature field, 10-30°C above the baseline temperature of 37°C. The experimental studies have demonstrated the capability of confining laser energy in tumors by a very small amount of nanorod solution.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
L. Zhu, A. Attaluri, H. Cai, R. Edziah, E. Lalanne, C. Bieberich, R. Ma, A. M. Johnson, "Temperature elevations in prostatic tumors during laser photothermal therapy", Proc. SPIE 8025, Smart Biomedical and Physiological Sensor Technology VIII, 80250G (26 May 2011); doi: 10.1117/12.882746; https://doi.org/10.1117/12.882746
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KEYWORDS
Tumors

Nanorods

Laser therapeutics

Temperature metrology

Gold

Laser energy

Laser tissue interaction

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