13 May 2011 Graphene field-effect transistors for label-free chemical and biological sensors
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Electrical detection of solution pH, protein adsorption and specific biomolecules were demonstrated by using graphene field-effect transistors (G-FETs). The monolayer graphene flakes were used as channel, which were obtained by conventional mechanical exfoliation from bulk graphite. The transport characteristics shifted to the positive voltage direction with increasing solution pH. The drain current changed by desorption of the charged protein. Moreover, we immobilized aptamers on the graphene surface. As a result, specific immunoglobulin sensing can be carried out using aptamer-modified G-FETs. These results strongly suggested that the G-FETs have high potentials for chemical and biological sensors.
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Yasuhide Ohno, Yasuhide Ohno, Kenzo Maehashi, Kenzo Maehashi, Kazuhiko Matsumoto, Kazuhiko Matsumoto, } "Graphene field-effect transistors for label-free chemical and biological sensors", Proc. SPIE 8031, Micro- and Nanotechnology Sensors, Systems, and Applications III, 803121 (13 May 2011); doi: 10.1117/12.882859; https://doi.org/10.1117/12.882859

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