Photonic crystal microarray nanoplatform for high throughput detection of biomolecules

Swapnajit Chakravarty; Wei-Cheng Lai; Kathryn Moncivais; Xiaolong Wang; Che-Yun Lin; Zhiwen J. Zhang; Ray T. Chen

doi:10.1117/12.882899

19 May 2011 Photonic crystal microarray nanoplatform for high throughput detection of biomolecules

Swapnajit Chakravarty, Wei-Cheng Lai, Kathryn Moncivais, Xiaolong Wang, Che-Yun Lin, Zhiwen J. Zhang, Ray T. Chen

Proceedings Volume 8034, Photonic Microdevices/Microstructures for Sensing III; 803402 (2011) https://doi.org/10.1117/12.882899
Event: SPIE Defense, Security, and Sensing, 2011, Orlando, Florida, United States

Abstract

We present preliminary designs and experimental results for creating a microarray nanoplatform based on twodimensional photonic crystal devices in silicon. Multiple photonic crystal microcavities are coupled along the length of a single photonic crystal waveguide that undergo resonance wavelength shifts when an antibody-antibody binding event occurs in the immediate vicinity of the corresponding photonic crystal microcavity. The microarray nanoplatform enables high throughput measurements of multiple antibody-antibody interactions via a single optical waveguide transmission measurement.

Citation Download Citation

Swapnajit Chakravarty, Wei-Cheng Lai, Kathryn Moncivais, Xiaolong Wang, Che-Yun Lin, Zhiwen J. Zhang, and Ray T. Chen "Photonic crystal microarray nanoplatform for high throughput detection of biomolecules", Proc. SPIE 8034, Photonic Microdevices/Microstructures for Sensing III, 803402 (19 May 2011); https://doi.org/10.1117/12.882899

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