19 May 2011 Photonic crystal microarray nanoplatform for high throughput detection of biomolecules
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We present preliminary designs and experimental results for creating a microarray nanoplatform based on twodimensional photonic crystal devices in silicon. Multiple photonic crystal microcavities are coupled along the length of a single photonic crystal waveguide that undergo resonance wavelength shifts when an antibody-antibody binding event occurs in the immediate vicinity of the corresponding photonic crystal microcavity. The microarray nanoplatform enables high throughput measurements of multiple antibody-antibody interactions via a single optical waveguide transmission measurement.
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Swapnajit Chakravarty, Wei-Cheng Lai, Kathryn Moncivais, Xiaolong Wang, Che-Yun Lin, Zhiwen J. Zhang, Ray T. Chen, "Photonic crystal microarray nanoplatform for high throughput detection of biomolecules", Proc. SPIE 8034, Photonic Microdevices/Microstructures for Sensing III, 803402 (19 May 2011); doi: 10.1117/12.882899; https://doi.org/10.1117/12.882899

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