14 June 2011 Simultaneous imaging of haemoglobin oxygenation and blood flow with RGB reflectometry and LASCA during stroke in rats
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Abstract
We demonstrate the simultaneous mapping of haemoglobin oxygenation and blood flow changes of human skin and the exposed cortex in rats by broad-band reflectometry and laser speckle contrast analysis (LASCA). A hard- and software set-up is realized with a high temporal resolution achieved by techniques of multi- and manycore computing. Spatial and temporal resolved changes of haemoglobin oxygenation and blood flow in rats are observed in response to middle cerebral artery occlusion and cortical spreading depression.
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A. Steimers, M. Gramer, M. Takagaki, R. Graf, M. Kohl-Bareis, "Simultaneous imaging of haemoglobin oxygenation and blood flow with RGB reflectometry and LASCA during stroke in rats", Proc. SPIE 8088, Diffuse Optical Imaging III, 808808 (14 June 2011); doi: 10.1117/12.889438; https://doi.org/10.1117/12.889438
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