8 June 2011 Soft tissue ablation by picosecond synchronously-pumped CdSiP2-based optical parametric oscillator tuned to 6.45 μm
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Abstract
Optical parametric oscillators (OPOs) are attractive tools for research on tissue ablation upon infrared irradiation. Here, we report on the performance of several mid-infrared nonlinear crystals, namely type I and type II AgGaS2 (AGS) and type I CdSiP2 (CSP), used in synchronously-pumped OPOs tuned to a wavelength of 6.45 μm, coinciding with the amide II absorption band of proteins. CSP-based OPOs clearly exhibit better performance in comparison to AGS: First, the oscillation threshold with CSP is three (five) times lower than type II (type I) AGS. Second, the idler conversion efficiency is more favourable for CSP and allows reaching 27.5 mW of idler average power, while 13 and 6 mW are obtained with type II and type I AGS, respectively. Such performance makes CSP suitable for high power 6.45 μm surgical applications. Preliminary ablation experiments on liver tissues with our CSP-based OPO highlight the promising future of CSP in medical applications.
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Nordine Hendaoui, Alaa Addin Mani, Ernest Kakudgi, André Peremans, Christophe Silien, Vincent Bruyninckx, Adolfo Esteban, Majid Ebrahim-Zadeh, Stefan Been, Rudolf M. Verdaasdonk, Peter G. Schunemann, Kevin T. Zawilski, Valentin Petrov, "Soft tissue ablation by picosecond synchronously-pumped CdSiP2-based optical parametric oscillator tuned to 6.45 μm", Proc. SPIE 8092, Medical Laser Applications and Laser-Tissue Interactions V, 80921R (8 June 2011); doi: 10.1117/12.889998; https://doi.org/10.1117/12.889998
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KEYWORDS
Optical parametric oscillators

Silver

Laser ablation

Tissues

Free electron lasers

Absorption

Nonlinear crystals

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