22 August 2011 Sensitivity of light interaction computer model to the absorption properties of skin
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Light based treatments offer major benefits to patients. Many of the light based treatments or diagnostic techniques need to penetrate the skin to reach the site of interest. Human skin is a highly scattering medium and the melanin in the epidermal layer of the skin is a major absorber of light in the visible and near infrared wavelength bands. The effect of increasing absorption in the epidermis is tested on skin simulating phantoms as well as on a computer model. Changing the absorption coefficient between 0.1 mm-1 and 1.0 mm-1 resulted in a decrease of light reaching 1 mm into the sample. Transmission through a 1 mm thick sample decreased from 48% to 13% and from 31% to 2% for the different scattering coefficients.
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A. E. Karsten, A. E. Karsten, A. Singh, A. Singh, } "Sensitivity of light interaction computer model to the absorption properties of skin", Proc. SPIE 8192, International Symposium on Photoelectronic Detection and Imaging 2011: Laser Sensing and Imaging; and Biological and Medical Applications of Photonics Sensing and Imaging, 81924Z (22 August 2011); doi: 10.1117/12.900550; https://doi.org/10.1117/12.900550

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