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5 December 2011 Bimetallic chips for SMX sensing in a surface plasmon resonance instrument
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Proceedings Volume 8198, 2011 International Conference on Optical Instruments and Technology: Optoelectronic Devices and Integration; 81980J (2011) https://doi.org/10.1117/12.904715
Event: International Conference on Optical Instruments and Technology (OIT2011), 2011, Beijing, Beijing, China
Abstract
We replace a commonly used Au film with an Au/Ag bimetallic film working as the sensing chip in the commercial surface plasmon resonance (SPR) instrument, Biacore 3000. The bimetallic chip gives out sharper SPR dip than that by the chip made of an Au film which can improve the sensitivity and accuracy. The applicability and stability of the bimetallic chip on the Biacore 3000 are tested by real-time monitoring of biological coupling processes between Sulfamethoxazole (SMX) and anti-SMX. The limit of detection of SMX is 1.8ng/ml.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yong Chen, Yonghua Lu, Douguo Zhang, Pei Wang, and Hai Ming "Bimetallic chips for SMX sensing in a surface plasmon resonance instrument", Proc. SPIE 8198, 2011 International Conference on Optical Instruments and Technology: Optoelectronic Devices and Integration, 81980J (5 December 2011); https://doi.org/10.1117/12.904715
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