9 February 2012 Deep skin structural and microcirculation imaging with extended-focus OCT
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Abstract
We present an extended focus OCT system for dermatologic applications that maintains high lateral resolution over a large depth range by using Bessel beam illumination. More, Bessel beams exhibit a self-reconstruction property that is particularly useful to avoid shadowing from surface structures such as hairs. High lateral resolution and high-speed measurement, thanks to a rapidly tuning swept source, allows not only for imaging of small skin structures in depth but also for comprehensive visualization of the small capillary network within the human skin in-vivo. We use this information for studying temporal vaso-responses to hypothermia. In contrast to other perfusion imaging methods such as laser Doppler imaging (LDI), OCT gives specific access to vascular responses in different vascular beds in depth.
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Cedric Blatter, Cedric Blatter, Branislav Grajciar, Branislav Grajciar, Robert Huber, Robert Huber, Rainer A. Leitgeb, Rainer A. Leitgeb, } "Deep skin structural and microcirculation imaging with extended-focus OCT", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82070B (9 February 2012); doi: 10.1117/12.909830; https://doi.org/10.1117/12.909830
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