Multiphoton tomography of intratissue tattoo nanoparticles

Karsten König

doi:10.1117/12.908128

9 February 2012 Multiphoton tomography of intratissue tattoo nanoparticles

Karsten König

Proceedings Volume 8207, Photonic Therapeutics and Diagnostics VIII; 82070S (2012) https://doi.org/10.1117/12.908128
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Most of today's intratissue tattoo pigments are unknown nanoparticles. So far, there was no real control of their use due to the absence of regulations. Some of the tattoo pigments contain carcinogenic amines e.g. azo pigment Red 22. Nowadays, the European Union starts to control the administration of tattoo pigments. There is an interest to obtain information on the intratissue distribution, their interaction with living cells and the extracellular matrix, and the mechanisms behind laser tattoo removal. Multiphoton tomographs are novel biosafety and imaging tools that can provide such information non-invasively and without further labeling. When using the spectral FLIM module, spatially-resolved emission spectra, excitation spectra, and fluorescence lifetimes can pr provided. Multiphoton tomographs are used by all major cosmetic comapanies to test the biosafety of sunscreen nanoparticles.

Citation Download Citation

Karsten König "Multiphoton tomography of intratissue tattoo nanoparticles", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82070S (9 February 2012); https://doi.org/10.1117/12.908128

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