Real-time line-scanning reflectance confocal endoscope to enhance sectioning and reduce speckle for intraoral imaging

Christopher Glazowski; Sanjeewa Abeytunge; Milind Rajadhyaksha

doi:10.1117/12.908283

9 February 2012 Real-time line-scanning reflectance confocal endoscope to enhance sectioning and reduce speckle for intraoral imaging

Christopher Glazowski, Sanjeewa Abeytunge, Milind Rajadhyaksha

Author Affiliations +

Proceedings Volume 8207, Photonic Therapeutics and Diagnostics VIII; 82071U (2012) https://doi.org/10.1117/12.908283
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

The line-scanning confocal microscope is simpler than a point-scanning confocal microscope and allows for a smaller and lower cost footprint, making it attractive for endoscopic clinical use. The optical configuration affects image fidelity. Here, we present a benchtop version of an endoscopic line-scanning confocal microscope for intraoral imaging, with a divided pupil and optimal detection configuration (magnification, pixel-to-resolution ratio) to enhance image fidelity. Improved sectioning performance and reduction of "speckle" noise are demonstrated. A topology for use of a deformable MEMs mirror-based optical axial focus control for imaging in depth is presented. Preliminary images of human oral mucosa in vivo demonstrate feasibility for clinical application.

Citation Download Citation

Christopher Glazowski, Sanjeewa Abeytunge, and Milind Rajadhyaksha "Real-time line-scanning reflectance confocal endoscope to enhance sectioning and reduce speckle for intraoral imaging", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82071U (9 February 2012); https://doi.org/10.1117/12.908283

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