9 February 2012 Wavelength multiplexing for FD-OCT speckle averaging
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Abstract
Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging. We demonstrate this technique using in vivo intravascular optical frequency domain imaging (OFDI) data.
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Gijs van Soest, Gijs van Soest, Evelyn Regar, Evelyn Regar, Brett E. Bouma, Brett E. Bouma, Guillermo J. Tearney, Guillermo J. Tearney, Antonius F. W. van der Steen, Antonius F. W. van der Steen, } "Wavelength multiplexing for FD-OCT speckle averaging", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 820742 (9 February 2012); doi: 10.1117/12.906335; https://doi.org/10.1117/12.906335
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