17 February 2012 Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study
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Abstract
Rupture of intracranial aneurysm is a common cause of subarachnoid hemorrhage. An aneurysm may undergo microscopic morphological changes or remodeling of the vessel wall prior to rupture, which could potentially be imaged. In this study we present methods of tissue sample preparation of intracranial aneurysms and correlation between optical coherence tomography imaging and routine histology. OCT has a potential future in the assessment of microscopic features of aneurysms, which may correlate to the risk of rupture.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Barry Vuong, Barry Vuong, Cuiru Sun, Cuiru Sun, Tim-Rasmus Khiel, Tim-Rasmus Khiel, Joseph A. Gardecki, Joseph A. Gardecki, Beau A. Standish, Beau A. Standish, Leodante da Costa, Leodante da Costa, Josaphat de Morais, Josaphat de Morais, Guillermo J. Tearney, Guillermo J. Tearney, Victor X. D. Yang, Victor X. D. Yang, } "Feasibility and methodology of optical coherence tomography imaging of human intracranial aneurysms: ex vivo pilot study", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82074M (17 February 2012); doi: 10.1117/12.908998; https://doi.org/10.1117/12.908998
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