9 March 2012 Accurate dosimetry for monitoring response to photodynamic therapy
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Abstract
Photodynamic therapy (PDT) is becoming a treatment of choice for cancer because of its low cost, high effectiveness and low damage to healthy tissue. Successful PDT outcome depends on accurate dosimetry, which is currently lacking, leading to variable and/or ineffective treatment outcome. We report on our research and developmental efforts towards an implicit dosimetric method for PDT that will provide an accurate assessment of treatment effectiveness by continuous monitoring of the in vivo drug concentration and the oxygen concentration in tissue. This approach uses the same tools presently available for PDT, making it attractive to the health professionals without increasing treatment cost.
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M. Seetamraju, M. Seetamraju, R. S. Gurjar, R. S. Gurjar, R. Myers, R. Myers, T. Hasan, T. Hasan, D. E. Wolf, D. E. Wolf, } "Accurate dosimetry for monitoring response to photodynamic therapy", Proc. SPIE 8210, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXI, 82100R (9 March 2012); doi: 10.1117/12.908836; https://doi.org/10.1117/12.908836
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