Adaptive optics: optical coherence tomography system for in-vivo imaging of the mouse retina

Yifan Jian; Ali Issaei; Robert J. Zawadzki; Marinko V. Sarunic

doi:10.1117/12.911489

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17 February 2012 Adaptive optics: optical coherence tomography system for in-vivo imaging of the mouse retina

Yifan Jian, Ali Issaei, Robert J. Zawadzki, Marinko V. Sarunic

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Proceedings Volume 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI; 82130L (2012) https://doi.org/10.1117/12.911489
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

We present a custom fourier domain optical coherence tomography imaging system for high resolution imaging of mouse retina. In order to overcome aberrations in the mouse eye, we incorporated an adaptive optics system into the sample arm of the OCT system. We used a refraction cancelling lens to minimize aberrations from the cornea, as well as reduce the specular back-reflection. Results of FDOCT images of mouse retina acquired in vivo with and without AO are presented.

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Yifan Jian, Ali Issaei, Robert J. Zawadzki, and Marinko V. Sarunic "Adaptive optics: optical coherence tomography system for in-vivo imaging of the mouse retina", Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 82130L (17 February 2012); https://doi.org/10.1117/12.911489

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