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17 February 2012 Doppler streak mode Fourier domain optical coherence tomography
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Abstract
Doppler Fourier domain optical coherence tomography is able to be used for in vivo blood flow measurement. In conventional methods, the highest velocity that can be measured is limited to the range the phase shift between two successively recorded depth profiles at the same probe-beam location, which cannot exceed (-π, π), otherwise phase wrapping will occur. This phase-wrapping limit is determined by the time interval between two consecutive A-scans. We present a novel approach to shorten the time interval between two consecutive A-scans and thus increase the phase-wrapping limit by using an area scan camera to record the interference spectrum in a streak mode. To demonstrate the effectiveness of this method, the blood flows in HH18 and HH19 chick hearts were imaged and phase wrapping free Doppler images were obtained.
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Rui Wang, Julie X. Yun, Richard Goodwin, Roger Markwald, Raymond B. Runyan, and Bruce Gao "Doppler streak mode Fourier domain optical coherence tomography", Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 82131H (17 February 2012); https://doi.org/10.1117/12.906418
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