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17 February 2012 Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography
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Abstract
Phase sensitive OCT enables the measurement of thermal expansion in laser irradiated material at high lateral and temporal resolution. In principle, a calculation of the 3D temperature distribution and its temporal evolution should be possible by evaluating the local expansion. This could be utilized for a non-invasive and very fast temperature measurement, e.g. to realize an online dosimetry for photocoagulation. The possibilities of quantitative investigations at high axial and lateral resolution are demonstrated by imaging the reversible thermal expansion in laser irradiated multilayer silicone phantoms.
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Hendrik Spahr, Linda Rudolph, Heike Müller, Reginald Birngruber, and Gereon Hüttmann "Imaging of photothermal tissue expansion via phase sensitive optical coherence tomography", Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 82131S (17 February 2012); https://doi.org/10.1117/12.911429
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