30 January 2012 Correction of phase-error for phase-resolved k-clocked optical frequency domain imaging
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Phase-resolved optical frequency domain imaging (OFDI) has emerged as a promising technique for blood flow measurement in human tissues. Phase stability is essential for this technique to achieve high accuracy in flow velocity measurement. In OFDI systems that use k-clocking for the data acquisition, phase-error occurs due to jitter in the data acquisition electronics. We presented a statistical analysis of jitter represented as point shifts of the k-clocked spectrum. We demonstrated a real-time phase-error correction algorithm for phase-resolved OFDI. A 50 KHz wavelength-swept laser (Axsun Technologies) based balanced-detection OFDI system was developed centered at 1310 nm. To evaluate the performance of this algorithm, a stationary gold mirror was employed as sample for phase analysis. Furthermore, we implemented this algorithm for imaging of human skin. Good-quality skin structure and Doppler image can be observed in real-time after phase-error correction. The results show that the algorithm can effectively correct the jitter-induced phase error in OFDI system.
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Jianhua Mo, Jianhua Mo, Jianan Li, Jianan Li, Johannes F. de Boer, Johannes F. de Boer, } "Correction of phase-error for phase-resolved k-clocked optical frequency domain imaging", Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 82132V (30 January 2012); doi: 10.1117/12.911570; https://doi.org/10.1117/12.911570

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