Time-domain diffuse fluorescence tomography of CT-analogous scheme: an experimental validation

Feng Gao; Weiting Chen; Jiao Li; Wei Zhang; Xi Yi; Xin Wang; Limin Zhang; Zhongxing Zhou; Huijuan Zhao

doi:10.1117/12.906986

29 February 2012 Time-domain diffuse fluorescence tomography of CT-analogous scheme: an experimental validation

Feng Gao, Weiting Chen, Jiao Li, Wei Zhang, Xi Yi, Xin Wang, Limin Zhang, Zhongxing Zhou, Huijuan Zhao

Proceedings Volume 8216, Multimodal Biomedical Imaging VII; 82160Y (2012) https://doi.org/10.1117/12.906986
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

A fiber-based non-contact scheme of the time-domain diffuse fluorescence yield and lifetime tomography is described that combines the time-correlated single photon counting technique for high-sensitive, time-resolved detection and CT-analogous configuration for high throughput data collection. A pilot validation of the methodology is performed for two-dimensional scenarios using simulated and experimental data. The results demonstrated the potential of the proposed scheme in improving the image quality.

Citation Download Citation

Feng Gao, Weiting Chen, Jiao Li, Wei Zhang, Xi Yi, Xin Wang, Limin Zhang, Zhongxing Zhou, and Huijuan Zhao "Time-domain diffuse fluorescence tomography of CT-analogous scheme: an experimental validation", Proc. SPIE 8216, Multimodal Biomedical Imaging VII, 82160Y (29 February 2012); https://doi.org/10.1117/12.906986

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