31 January 2012 Ultrafast time-dependent fluorescence spectroscopy for human breast cancer detection
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Proceedings Volume 8220, Optical Biopsy X; 82200X (2012) https://doi.org/10.1117/12.906254
Event: SPIE BiOS, 2012, San Francisco, California, United States
Abstract
Time-resolved fluorescence emission from normal breast tissue, benign and malignant breast tumors were measured using excitation of 100 fs pulses at 310nm. Fluorescence relaxation decay parameters were extracted from the measured temporal emission profiles. The decay times and amplitudes of fast and slow profiles of malignant tissues were different from normal and benign tissues, which allows the malignant tumor to be separated from non-malignant breast tissue. The differences between the decay times of slow and fast component can be explained by tissue structure changes during breast cancer evolution.
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Yang Pu, Yang Pu, Guichen Tang, Guichen Tang, B. B. Das, B. B. Das, C.-H. Liu, C.-H. Liu, Asima Pradhan, Asima Pradhan, Robert R. Alfano, Robert R. Alfano, "Ultrafast time-dependent fluorescence spectroscopy for human breast cancer detection", Proc. SPIE 8220, Optical Biopsy X, 82200X (31 January 2012); doi: 10.1117/12.906254; https://doi.org/10.1117/12.906254
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