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15 February 2012 Oxidase method for glucose determination using long-period grating waveguide
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Abstract
Possibility of photonic crystal fiber-based glucose sensor developing is discussed. We considered the concept of the use of chirped photonic crystal fiber with big grating period as a fiber refractometer and "smart" photometric cuvette, and possibility to combine refractometric and oxidase methods for glucose determination. Influence of refractive index change of the liquid medium, determined by significant increase of containing glucose, to spectral characteristics of photonic crystal fiber was studied and the optical response to insignificant change (tenths of millimoles per liter) of glucose concentration was obtained.
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A. V. Malinin, A. A. Zanishevskaja, V. V. Tuchin, Yu. S. Skibina, and I. Yu. Silokhin "Oxidase method for glucose determination using long-period grating waveguide", Proc. SPIE 8222, Dynamics and Fluctuations in Biomedical Photonics IX, 82221B (15 February 2012); https://doi.org/10.1117/12.914547
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