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9 February 2012 Non-invasive monitoring of vascularization of grafted engineered human oral mucosa
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Abstract
Accident victims and victims of explosive devices often suffer from complex maxillofacial injuries. The lips are one of the most difficult areas of the face to reconstruct after an avulsion. Lip avulsion results in compromised facial esthetics and functions of speech and mastication. The process of reconstruction requires assessment of the vascularization of grafted ex vivo engineered tissue while it is buried underneath the skin. We describe the design and animal testing of a hand-held surgical probe based upon diffuse correlation spectroscopy to assess vascularization.
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D. E. Wolf, M. Seetamraju, R. S. Gurjar, R. S. Kuo, A. Fasi, and S. E. Feinberg "Non-invasive monitoring of vascularization of grafted engineered human oral mucosa", Proc. SPIE 8222, Dynamics and Fluctuations in Biomedical Photonics IX, 82221D (9 February 2012); doi: 10.1117/12.909032; https://doi.org/10.1117/12.909032
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