13 February 2012 Multiphoton spectroscopy of human skin in vivo
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Abstract
In vivo multiphoton-intensity images and emission spectra of human skin are reported. Optical sections from different depths of the epidermis and dermis have been measured with near-infrared laser-pulse excitation. While the intensity images reveal information on the morphology, the spectra show emission characteristics of main endogenous skin fluorophores like keratin, NAD(P)H, melanin, elastin and collagen as well as of second harmonic generation induced by the excitation-light interaction with the dermal collagen network.
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Hans G. Breunig, Hans G. Breunig, Martin Weinigel, Martin Weinigel, Karsten König, Karsten König, } "Multiphoton spectroscopy of human skin in vivo", Proc. SPIE 8225, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X, 82251D (13 February 2012); doi: 10.1117/12.908227; https://doi.org/10.1117/12.908227
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